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Cardinals–Cubs rivalry

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Route 66 rivalry; Cardinals lead 11-3 in World Series titles; Cubs lead all-time series 1,091-1,044

From Wikipedia

The Cardinals–Cubs rivalry, also called the Route 66 rivalry and The I-55 rivalry, refers to the rivalry between the St. Louis Cardinals and Chicago Cubs of the National League (NL), one of the most bitter rivalries in Major League Baseball and in all of North American professional sports. The Cardinals have won 19 NL pennants, while the Cubs have won 17. However, the Cardinals have a clear edge when it comes to World Series success, having won 11 championships to the Cubs' three. Games between the two clubs see numerous visiting fans in either St. Louis's Busch Stadium or Chicago's Wrigley Field. When the NL split into two divisions in 1969, and later three divisions in 1994, the Cardinals and Cubs remained together.

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All-time
Cubs
Next meeting
May 29, 2026, Busch Stadium, St. Louis, Missouri
Total
2,543
Current streak
Cubs, 3
First meeting
October 14, 1885, Congress Street Grounds, Chicago, Illinois, Browns 5, White Stockings 5
Most recent
September 28, 2025, Wrigley Field, Chicago, Illinois, Cubs 2, Cardinals 0

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